Apolipoprotein A-I (apo A-I): is a protein that has a specific role in the metabolism of lipids and is the main protein component in high-density lipoprotein (HDL, the “good cholesterol”). This test measures the amount of apo A-I in the blood.
Apolipoprotein B: is the primary apolipoprotein of chylomicrons, VLDL, IDL, and LDL particles (LDL – known commonly by the misnomer “bad cholesterol” when in reference to both heart disease and vascular disease in general), which is responsible for carrying fat molecules (lipids), including cholesterol, around the body.
Apo tests are conducted to find out the risk one has towards cardiovascular diseases.
To get the diagnosis, doctors will test your blood to find out how long it takes to clot and to see if it’s missing any clotting factors. This often includes:
- Complete blood count (CBC). It gives important information about the kinds and numbers of cells in your blood.
- Prothrombin time (PT) and activated partial thromboplastin time (PTT). Both tests how long it takes blood to clot.
- Factor VIII and factor IX tests. These measure levels of the clotting factors.
Apolipoprotein levels are used to evaluate the risk of cardiovascular disease. The reference range of Apo levels in adults is less than 130 mg/dL (1.3 g/L). Apo levels are higher in males than in females and tend to increase with age.